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The harmala alkaloids are psychoactive and function as short-acting reversible inhibitors of MAO-A.
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Description
The seeds of Peganum harmala contain several alkaloids, mainly the harmala alkaloids harmine and harmaline. Other beta-carbolines are harmalol, harmane, harmidine, dihydro harmaline, isoharmine, tetrahydroharmine, tetrahydroharmaline, tetrahydroharmol, and norharmine.
Harmine, harmaline and tetrahydroharmine also occur in the ayahuasca vine Banisteriopsis caapi. The concentration is slightly higher in Syrian rue: approximately 2-7% of the dry weight of mature seeds.
The harmala alkaloids are psychoactive and function as short-acting reversible inhibitors of MAO-A. This means they suppress the excretion of the endogenous enzyme monoamine oxidase (MAO). This enzyme normally metabolizes certain endogenous neurotransmitters like serotonin, as well as foreign toxins (like tyramines in food) and tryptamines. When the enzyme is blocked, substances like N, N-DMT and 5-MeO-DMT become orally effective. The effect of others substances like mescaline, LSD and psilocybin is potentiated.
I have tried using this with the planty xany and really appreciated the difference in length it kept me in a cozy sleep state. I used 2tsp of the crushed seeds with 2 full droppers of planty xany. 15-25min after finishing my warm glass which I added a bit of honey for the taste( seeds were a little bitter) I felt warm fuzzy ness all over my legs and as I laid down went into a cozy and deep fuzzy sleep soon there after.. I have a lot of trouble with sleeping especially for very long periods of time. And so sleeping 6 hrs uninterrupted was quite s treat.. definitely added length and also the effect were a bit more intense when added. Enjoy