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The seeds of Peganum harmala contain several alkaloids, mainly the harmala alkaloids harmine and harmaline. Other beta-carbolines are harmalol, harmane, harmidine, dihydro harmaline, isoharmine, tetrahydroharmine, tetrahydroharmaline, tetrahydroharmol, and norharmine.
Harmine, harmaline and tetrahydroharmine also occur in the ayahuasca vine Banisteriopsis caapi. The concentration is slightly higher in Syrian rue: approximately 2-7% of the dry weight of mature seeds.
The harmala alkaloids are psychoactive and function as short-acting reversible inhibitors of MAO-A. This means they suppress the excretion of the endogenous enzyme monoamine oxidase (MAO). This enzyme normally metabolizes certain endogenous neurotransmitters like serotonin, as well as foreign toxins (like tyramines in food) and tryptamines. When the enzyme is blocked, substances like N, N-DMT and 5-MeO-DMT become orally effective. The effect of others substances like mescaline, LSD and psilocybin is potentiated.
Peganum Harmala extract: The extract contains 3.5 grams of crushed and extracted Rue seeds. The extraction process was for one month and the seeds were drained. use this to potentiate other entheogens by adding a couple droppers full to your warm solvent of choice and your micro-dose or planty zany. Peganum has a sedative effect if taken alone so you can also use this alone in hot tea.
Peganum crushed seeds: Add a tsp to your planty xany drink or a ceremony to potentiate effects and make them last longer. Peganum can be taken with any entheogen to active the psycho active effects. Do not take with synthetic chemicals such as MDMA, this can be very harmful. Only use Peganum with natural entheogens.